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Dr Nicolas Le Novere

Departments and Institutes

The Babraham Institute :

Research Interests

Le Novere lab uses bioinformatic methods and mathematical modelling to study the basic processes of life. Based on the information acquired from experiments and existing literature one can build mathematical models that can then be simulated under various conditions. The success or failure of reproducing observed behaviours tell us if we adequately understand the mechanisms of life. The main biological focus of the group is to understand how cellular and molecular systems interpret signals from their environment and adapt their behaviour as a consequence. This entails understanding how the various cells receive and transduce signals, the interplay of different signalling pathways, and the final outcome for cell physiology, including gene expression and cell fate.

Keywords

Mathematical Modelling ; Network Modelling ; Stem Cells ; Systems Biology ; Neuroscience