Dom Kirkham

PhD Student

Contact information

Biography

I’m a third year PhD student at the MRC Biostatistics Unit in the University of Cambridge, supervised by Oscar M. Rueda and Sach Mukherjee.

Research interests

My work focuses on the use of representation learning in cancer medicine. In particular, I am interested in constrained representations of omics data – regularising and constraining representations in order to improve robustness and performance in downstream tasks. These methods can also help us draw parallels between distinct datasets, using a dataset generated in one setting to improve models for others.

Within cancer biology, I'm interested in the effect of hormone therapies on cancer risk, treatment response, and progression, and also the development of hormone-based treatments for cancer.

Keywords

Computational biology, Data-driven medicine, Deep learning, Genomics, Healthcare, RNA-seq, Variational inference

Themes

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The Cambridge Centre for Data-Driven Discovery (C2D3) brings together researchers and expertise from across the academic departments and industry to drive research into the analysis, understanding and use of data science and AI. C2D3 is an Interdisciplinary Research Centre at the University of Cambridge.

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