Dom Kirkham
PhD Student
Contact information
Biography
I’m a third year PhD student at the MRC Biostatistics Unit in the University of Cambridge, supervised by Oscar M. Rueda and Sach Mukherjee.
Research interests
My work focuses on the use of representation learning in cancer medicine. In particular, I am interested in constrained representations of omics data – regularising and constraining representations in order to improve robustness and performance in downstream tasks. These methods can also help us draw parallels between distinct datasets, using a dataset generated in one setting to improve models for others.
Within cancer biology, I'm interested in the effect of hormone therapies on cancer risk, treatment response, and progression, and also the development of hormone-based treatments for cancer.
Keywords
Computational biology, Data-driven medicine, Deep learning, Genomics, Healthcare, RNA-seq, Variational inference